Clinical and translational cardiovascular medicine

Section edited by: Yong-Xiao Wang

The primary objective of this section is to promote significant enhancements in etiology, mechanistic understanding, prevention, diagnosis, and therapies of cardiovascular diseases. This section covers epidemiological investigations, clinical trials or observational studies, novel technologies or instruments, human biology, cell or animal models, mechanism investigations, genomics, biomarkers, bioengineering, bioinformatics, drug discovery and development, gene therapies, drug and gene deliveries, biomaterial utilization, and healthcare regulation or policy of all cardiovascular diseases, including but not limited to, heart attack, cardiac arrhythmias, heart failure, heart valve disease, congenital heart disease, heart muscle disease (cardiomyopathy), stroke, hypertension, coronary artery disease, atherosclerosis, pulmonary hypertension, and aneurysm.

  1. Review

    Mitochondrial transplantation for therapeutic use

    Mitochondria play a key role in the homeostasis of the vast majority of the body’s cells. In the myocardium where mitochondria constitute 30 % of the total myocardial cell volume, temporary attenuation or obst...

    James D. McCully, Sidney Levitsky, Pedro J. del Nido and Douglas B. Cowan

    Clinical and Translational Medicine 2016 5:16

    Published on: 29 April 2016

  2. Review

    Clinical significance of macrophage phenotypes in cardiovascular disease

    The emerging understanding of macrophage subsets and their functions in the atherosclerotic plaque has led to the consensus that M1 macrophages are pro-atherogenic while M2 macrophages may promote plaque stabi...

    Heather J Medbury, Helen Williams and John P Fletcher

    Clinical and Translational Medicine 2014 3:63

    Published on: 21 November 2014