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Clinical and translational cardiovascular medicine

Section edited by: Yong-Xiao Wang

The primary objective of this section is to promote significant enhancements in etiology, mechanistic understanding, prevention, diagnosis, and therapies of cardiovascular diseases. This section covers epidemiological investigations, clinical trials or observational studies, novel technologies or instruments, human biology, cell or animal models, mechanism investigations, genomics, biomarkers, bioengineering, bioinformatics, drug discovery and development, gene therapies, drug and gene deliveries, biomaterial utilization, and healthcare regulation or policy of all cardiovascular diseases, including but not limited to, heart attack, cardiac arrhythmias, heart failure, heart valve disease, congenital heart disease, heart muscle disease (cardiomyopathy), stroke, hypertension, coronary artery disease, atherosclerosis, pulmonary hypertension, and aneurysm.

  1. Content type: Review

    Considering the important role of microbiome, many of current investigations have focused on its beneficial aspects. Although, research explores new dimensions of the impact of microbiome and examines the diff...

    Authors: Ava Behrouzi, Amir Hossein Nafari and Seyed Davar Siadat

    Citation: Clinical and Translational Medicine 2019 8:16

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  2. Content type: Research

    Pulmonary endothelial cells’ (ECs) injury and apoptotic death are necessary and sufficient for the pathogenesis of the acute respiratory distress syndrome (ARDS), regardless of epithelial damage. Interaction o...

    Authors: Trushil Shah, Shanshan Qin, Mona Vashi, Dan N. Predescu, Niranjan Jeganathan, Cristina Bardita, Balaji Ganesh, Salvatore diBartolo, Louis F. Fogg, Robert A. Balk and Sanda A. Predescu

    Citation: Clinical and Translational Medicine 2018 7:19

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  3. Content type: Review

    Human Yippee-like-4 (YPEL4) is a member of the YPEL gene family. This family has been characterized as the first highly conserved family of genes coding for proteins that contain putative zinc-finger-like meta...

    Authors: Lillian Truong, Yun-Min Zheng, Tengyao Song, Yi Tang and Yong-Xiao Wang

    Citation: Clinical and Translational Medicine 2018 7:16

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  4. Content type: Research

    Fetuin-A is a multifunctional circulating glycoprotein that can induce insulin resistance. Lately, adipose tissue has gained prominence as an effector site of fetuin-A. Although fetuin-A—induced proinflammator...

    Authors: Saori Maruo, Katsuhito Mori, Koka Motoyama, Miyuki Nakamura, Reina Kawarabayashi, Yoshinori Kakutani, Yuko Yamazaki, Tomoaki Morioka, Tetsuo Shoji, Masaaki Inaba and Masanori Emoto

    Citation: Clinical and Translational Medicine 2018 7:9

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  5. Content type: Research

    Recently, non-vitamin K antagonist oral anticoagulants such as direct thrombin and direct factor Xa inhibitors have been prescribed for prevention of embolic stroke. While in Japan, argatroban, also a direct t...

    Authors: Taizen Nakase, Junta Moroi and Tatsuya Ishikawa

    Citation: Clinical and Translational Medicine 2018 7:2

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  6. Content type: Review

    Mitochondria play a key role in the homeostasis of the vast majority of the body’s cells. In the myocardium where mitochondria constitute 30 % of the total myocardial cell volume, temporary attenuation or obst...

    Authors: James D. McCully, Sidney Levitsky, Pedro J. del Nido and Douglas B. Cowan

    Citation: Clinical and Translational Medicine 2016 5:16

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