Guillausseau PJ, Meas T, Virally M, Laloi-Michelin M, Médeau V, Kevorkian JP. Abnormalities in insulin secretion in type 2 diabetes mellitus. Diabetes Metab. 2008;34 Suppl 2:S43–8.
Article
CAS
PubMed
Google Scholar
International Diabetes Federation. IDF Diabetes Atlas. 6th ed. Brussels, 2013. Available at: http://www.idf.org/diabetesatlas. Accessed: September 30, 2014.
Seshasai SRK, Kaptoge S, Thompson A, Di Angekantinio E, Gao P, Sarwar N, et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med. 2011;364(9):829–41.
Article
CAS
PubMed
Google Scholar
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 2007;445(7130):881–5.
Article
CAS
PubMed
Google Scholar
Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, et al. TCF7L2 is a master regulator of insulin production and processing. Hum Mol Genet. 2014;23(24):6419–31.
Article
PubMed Central
CAS
PubMed
Google Scholar
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjogren M, et al. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in non-diabetic individuals. Diabetes. 2006;55(10):2890–5.
Article
CAS
PubMed
Google Scholar
Loss RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, et al. TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population. Diabetes. 2007;56:1943–7.
Article
Google Scholar
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320–3.
Article
CAS
PubMed
Google Scholar
Berhouma R, Kouidhi S, Ammar M, Abid H, Barouti T, Ennafaa H, et al. Genetic susceptibility to type 2 diabetes: a global meta-analysis studying the genetic differences in Tunisian populations. Hum Biol. 2012;84(4):423–35.
Article
PubMed
Google Scholar
Tong Y, Lin Y, Zhang Y, Yang J, Zhang Y, Liu H, et al. Association between TCFL2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis. BMC Med Genet. 2009;10:15.
Article
PubMed Central
PubMed
Google Scholar
Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohan Krishna P, Hattersley AT, et al. Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia. 2007;50(1):63–7.
Article
CAS
PubMed
Google Scholar
Bodhini D, Radha V, Dhar M, Narayani N, Mohan V. The rs12255372 (G/T) and rs7903146 (C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians. Metabolism. 2007;56(9):1174–8.
Article
CAS
PubMed
Google Scholar
Alami FM, Ahmadi M, Bazrafshan H, Tabarraei A, Khosravi A, Tabatabaiefar MA, et al. Association of the TCF7L2 rs12255372 (G/T) variant with type 2 diabetes mellitus in an Iranian population. Genet Mol Biol. 2012;35(2):413–7.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hayashi T, Iwamoto Y, Kaku K, Hirose H, Maeda S. Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia. 2007;50:980–4.
Article
CAS
PubMed
Google Scholar
Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, et al. Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes. 2006;55:2649–53.
Article
CAS
PubMed
Google Scholar
Saadi H, Nagelkerke N, Carruthers SG, Benedict S, Abdulkhalek S, Reed R, et al. Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects. Diabetes Res Clin Pract. 2008;80:392–8.
Article
CAS
PubMed
Google Scholar
Wangs J, Kuusisto J, Vanttinen M, Kuulasmaa T, Lindstrom J, Tuomilehto J, et al. Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia. 2007;50:1192–200.
Article
Google Scholar
Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, et al. Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes. 2007;56:2631–7.
Article
CAS
PubMed
Google Scholar
Alsmadi O, Al-Rubeaan K, Mohamed G, Alkayal F, Al-Saud H, Al-Saud NA, et al. Weak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population. BMC Med Genet. 2008;9:e72.
Article
Google Scholar
Guo T, Hanson RL, Traurig M, Muller YL, Ma L, Mack J, et al. TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: Analysis of 3,501 individuals. Diabetes. 2007;2007(56):3082–8.
Article
Google Scholar
Pirie FJ, Motala AA, Pegoraro RJ, Paruk IM, Govender T, Rom L. Variants in PPARG, KCNJ11, TCF7L2, FTO, and HHEX genes in South African subjects of Zulu descent with type 2 diabetes. Afr J Diab Med. 2010;18(1):12–6.
Google Scholar
WHO-IDF. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: report of a WHO/IDF consultation. Available at: http://www.idf.org/webdata/docs/WHO_IDF_definition_diagnosis_of_diabetes.pdf. Accessed: October 1, 2014.
Friedewald WT, Levy RI, Fredrickson DS. Estimation of low density lipoprotein cholesterol without the use of the preparative ultracentrifuge. Clin Chem. 1972;18(6):499–502.
CAS
PubMed
Google Scholar
Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems T. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. Am J Trop Med Hyg. 1995;52:565–8.
CAS
PubMed
Google Scholar
H3Africa Consortium. Research capacity. Enabling the genomic revolution in Africa. Science. 2014;344(6190):1346–8.
Article
Google Scholar
Včelák J, Vejražková D, Vaňková M, Lukášová P, Bradnová O, Hálková T, et al. T2D Risk haplotypes of the TCF7L2 gene in the Czech population sample: the association with free fatty acids composition. Physiol Res. 2012;61(3):229–40.
PubMed
Google Scholar
Helgason A, Pálsson S, Thorleifsson G, Grant SF, Emilsson V, Gunnarsdottir S, et al. Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet. 2007;39(2):218–25.
Article
CAS
PubMed
Google Scholar
Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, et al. Variants of the Transcription Factor 7-Like 2 (TCF7L2) gene are associated with type 2 diabetes in an African American population enriched for nephropathy. Diabetes. 2007;56(10):2638–42.
Article
CAS
PubMed
Google Scholar
Elston RC, Forthofer R. Testing for Hardy-Wainberg equilibrium in small samples. Biometrics. 1977;33(3):536–42.
Article
Google Scholar