Table 2 Association between the TCF7L2 rs12255372 (G/T) polymorphism with type 2 diabetes mellitus
rs12255372 (G/T) | Controls, n (%) | T2DM, n (%) | OR (95% CI) | p value |
|---|---|---|---|---|
Alleles | ||||
G | 95 (83.33) | 65 (56.03) | / | / |
T | 19 (16.7) | 51 (43.96) | 3.92 (2.04 – 7.67) | 0.0001 |
Total (2 N) | 114 | 116 | ||
Genotypes | ||||
GG | 46 (80.7) | 31 (53.44) | / | |
GT | 3 (5.26) | 3 (5.17) | 1.48 (0.18 – 11.75) | 0.68 |
TT | 8 (14.03) | 24 (41.37) | 4.45 (1.64 – 12.83)/4.33* (1.57 – 11.92) | 0.0014/0.005* |
Total (N) | 57 | 58 |