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Table 5 New drugs (DAA combinations) for the treatment of hepatitis C in phase II study

From: Treatment of hepatitis C virus infection in the future

Drug name/category

Drug name/category

Company

ABT-450r/Protease inhibitor

ABT-072/Polymerase inhibitor

Abbott/Enanta

ABT-450r/Protease inhibitor

ABT-267/NS5A inhibitor

Abbott/Enanta

ABT-450r/Protease inhibitor

ABT-333/Polymerase inhibitor

Abbott/Enanta

Daclatasvir (BMS-79002)/ NS5A inhibitor

Sofosbuvir (GS-7977)/ Polymerase inhibitor

Bristol-Myers Squibb/Gilead

Daclatasvir (BMS-79002)/ NS5A inhibitor

Simeprevir (TMC435)/ Protease inhibitor

Bristol-Myers Squibb/Janssen

Danoprevir (RG7227)/ Protease inhibitor

Setrobuvir (ANA 598)/ Polymerase inhibitor

Genentech

Danoprevir (RG7227)/ Protease inhibitor

Mericitabine (RG7128)/ Polymerase inhibitor

Genentech

GS-9256

Tegobuvir (GS-9190)/ Polymerase inhibitor

Gilead

Incivek (Telaprevir)/ Protease inhibitor

VX-222/Polymerase inhibitor

Vertex

Mericitabine (RG7128)/ Polymerase inhibitor

Incivek (Telaprevir)/ Protease inhibitor

Genentech/Vertex

Simeprevir (TMC435)/ Protease inhibitor

Daclatasvir (BMS-79002)/ NS5A inhibitor

Janssen/Bristol-Myers Squibb

Simeprevir (TMC435)/ Protease inhibitor

Sofosbuvir (GS-7977)/ Polymerase inhibitor

Janssen/ Gilead

Simeprevir (TMC435)/ Protease inhibitor

TMC647055/NNI inhibitor/Ritonavir

Janssen

Sofosbuvir (GS-7977)/ Polymerase inhibitor

GS-5885/ NS5A inhibitor

Gilead

VX-135/Polymerase inhibitor

GSK2336805/ NS5A inhibitor

Vertex/GSK

VX-135/Polymerase inhibitor

Simeprevir (TMC435)/ Protease inhibitor

Vertex/Janssen

  1. HCV advocate: http://hcvadvocate.blogspot.ca/p/quick-reference-guide_21.html accessed on 2013/2/24.