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Table 6 Risk factors for liver relapse postoperatively

From: Prediction of hepatic metastasis and relapse in colorectal cancers based on concordance analyses with liver fibrosis scores

Variables

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

P value

Hazard ratio

95% CI

P value

Liver fibrosis score

 NFS

2.42

1.565–3.743

< 0.001

1.488

1.086–2.039

0.013

 FIB-4

1.387

1.018–1.890

0.038

1.368

1.004–1.864

0.047

 APRI

1.156

0.872–1.532

0.313

   

CRS

 ≤ 2

Reference

  

Reference

  

 > 2

1.995

1.502–2.651

< 0.001

1.952

1.469–2.595

< 0.001

 Male gender

0.856

0.647–1.133

0.278

   

 Age > 70

1.41

0.904–2.198

0.13

   

T stage

 T1

Reference

     

 T2

0.644

0.260–1.595

0.341

   

 T3

0.829

0.378–1.815

0.639

   

 T4

0.795

0.371–1.705

0.556

   

N stage

 N0

Reference

     

 N positive

0.888

0.737–1.069

0.209

   

Location

 Right-sided colon

Reference

     

 Left-sided colon

1.387

0.917–2.097

0.121

   

 Rectum

1.425

0.986–2.059

0.059

   

Lymph node examined

0.983

0.963–1.004

0.108

   

Mucinous Adenocarcinoma

1.762

0.958–3.241

0.069

   

Perineural invasion

1.124

0.826–1.528

0.457

   

Vascular invasion

1.068

0.783–1.457

0.678

   

CEA

1.557

1.168–2.075

0.003

1.346

1.003–1.808

0.048

Diabetes mellitus

1.074

0.676–1.706

0.763

   

Obesity (BMI > 25)

1.269

0.909–1.770

0.162

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