Fig. 5
From: PI3K inhibitor treatment ameliorates the glucocorticoid insensitivity of PBMCs in severe asthma
The effect of the PI3K inhibitor alone and in combination with dexamethasone on IL-8 release in the H2O2-TNFα-U937 cell model. a The IL-8 concentration was upon the addition of dexamethasone, BEZ235, and LY294002 was measured by ELISA. b The IL-8 concentration upon the addition of DEX + BEZ235 or DEX + LY294002 was measured by ELISA (*p < 0.05; **p < 0.01, ns: nonsignificant. Each experiment was repeated at least three times)