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Table 2 Association between cf DNA concentration (ng/mL) and patients’ characteristics

From: Circulating free DNA concentration as a marker of disease recurrence and metastatic potential in lung cancer

  cfDNA concentration (MN kit) (ng/ml) P value cfDNA concentration (QIAGEN kit) (ng/ml) P value
Gender
Male vs. female 13.96 (4.67) vs. 13.88 (3.69) 0.94 19.21 (6.59) vs. 19.01 (5.67) 0.91
Smoking
Yes vs. no 13.96 (4.55) vs. 13.9 (4.05) 0.97 19.17 (6.1) vs. 19.08 (6.1) 0.96
Current status
Alive vs. dead 13.22 (4.56) vs. 16.21 (3.4) 0.05 17.56 (5.78) vs. 23.49 (6.28) 0.007
Recurrence
Yes vs. no 15.81 (3.45) vs. 12.06 (4.7) 0.008 21.93 (6.09) vs. 16.27 (5.7) 0.007
Stage
II and III vs. IV 7.66 (2.5) vs. 14.37 (3.84) 0.005 11.43 (2.05) vs. 19.66 (5.84) 0.02
Metastasis
Non metastatic vs. Metastasis to one organ 7.94 (3.81) vs. 13.69 [3] 0.02 11.1 (3.52) vs. 18.71 (4.73) 0.01
Non metastatic vs. Metastasis to two organs 7.94 (3.81) vs. 16.5 (2.29) 0.001 11.1 (3.52) vs. 23.5 (4.98) 0.002
Non metastatic vs. Metastasis to three organ 7.94 (3.81) vs. 19.18 (3.45) < 0.001 11.1 (3.52) vs. 25.92 (6.24) < 0.001
Metastasis to one organ vs. Metastasis to two organs 13.69 [3] vs. 16.5 (2.29) 0.33 18.71 (4.73) vs. 23.5 (4.98) 0.26
Metastasis to one organ vs. Metastasis to three organs 13.69 [3] vs. 19.18 (3.45) 0.004 18.71 (4.73) vs. 25.92 (6.24) 0.01
Metastasis to two organs vs. Metastasis to three organs 16.5 (2.29) vs. 19.18 (3.45) 0.57 23.5 (4.98) vs. 25.92 (6.24) 0.87