Table 2 Association between cf DNA concentration (ng/mL) and patients’ characteristics
cfDNA concentration (MN kit) (ng/ml) | P value | cfDNA concentration (QIAGEN kit) (ng/ml) | P value | |
|---|---|---|---|---|
Gender | ||||
Male vs. female | 13.96 (4.67) vs. 13.88 (3.69) | 0.94 | 19.21 (6.59) vs. 19.01 (5.67) | 0.91 |
Smoking | ||||
Yes vs. no | 13.96 (4.55) vs. 13.9 (4.05) | 0.97 | 19.17 (6.1) vs. 19.08 (6.1) | 0.96 |
Current status | ||||
Alive vs. dead | 13.22 (4.56) vs. 16.21 (3.4) | 0.05 | 17.56 (5.78) vs. 23.49 (6.28) | 0.007 |
Recurrence | ||||
Yes vs. no | 15.81 (3.45) vs. 12.06 (4.7) | 0.008 | 21.93 (6.09) vs. 16.27 (5.7) | 0.007 |
Stage | ||||
II and III vs. IV | 7.66 (2.5) vs. 14.37 (3.84) | 0.005 | 11.43 (2.05) vs. 19.66 (5.84) | 0.02 |
Metastasis | ||||
Non metastatic vs. Metastasis to one organ | 7.94 (3.81) vs. 13.69 [3] | 0.02 | 11.1 (3.52) vs. 18.71 (4.73) | 0.01 |
Non metastatic vs. Metastasis to two organs | 7.94 (3.81) vs. 16.5 (2.29) | 0.001 | 11.1 (3.52) vs. 23.5 (4.98) | 0.002 |
Non metastatic vs. Metastasis to three organ | 7.94 (3.81) vs. 19.18 (3.45) | < 0.001 | 11.1 (3.52) vs. 25.92 (6.24) | < 0.001 |
Metastasis to one organ vs. Metastasis to two organs | 13.69 [3] vs. 16.5 (2.29) | 0.33 | 18.71 (4.73) vs. 23.5 (4.98) | 0.26 |
Metastasis to one organ vs. Metastasis to three organs | 13.69 [3] vs. 19.18 (3.45) | 0.004 | 18.71 (4.73) vs. 25.92 (6.24) | 0.01 |
Metastasis to two organs vs. Metastasis to three organs | 16.5 (2.29) vs. 19.18 (3.45) | 0.57 | 23.5 (4.98) vs. 25.92 (6.24) | 0.87 |