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Clinical and Translational Medicine

Table 1 Mutation rate in human cancers

From: Analyses of repeated failures in cancer therapy for solid tumors: poor tumor-selective drug delivery, low therapeutic efficacy and unsustainable costs

Cancer type

Mutation/tumor

Respiratory/lung cancer

200–300

Skin/melanoma

100–200

Esophageal/colon cancer

50–100

Pancreatic, ovarian

30–60

Breast

20–70

Hematopoietic cancer

1–10

(CML/AML/ALL/CLL) rhabdo/myo/sarcoma

1–3

  1. Mutations of tumor cells were based on means of mutation in single patients
  2. (CML/AML/ALL/CLL) Soft tissue/rhadomyoscarcoma
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