Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia

Clinical and Translational Medicine

Table 6 Copy number variants unique to the affected member of family 1 (I-2-1)

Chr	Start	End	Cytoband	Size (bp)	CNV type	Identity	Overlapping genes
5	119380128	119382128	5q23.1	2000	Del	De novo	None
9	6700000	6710000	9p24.1	10,000	Del	De novo	None
10	26998675	27002675	10p12.1	4000	Del	De novo	PDSS1
14	20314000	20328000	14q11.2	14,000	Amp	Inherited	None
15	22422114	22492114	15q11.2	70,000	Amp	De novo	LOC642131
16	34467150	34515150	16p11.2	48,000	Amp	De novo	None
16	55841801	55855801	16q12.2	14,000	Amp	Inherited	CES1

The parental sequences have been used to establish the de novo [absent in parent(s)] or inherited [also present in parent(s)] nature of each CNV. Shared identity is based on a 50% reciprocal overlap rule