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Clinical and Translational Medicine
Fig. 2 | Clinical and Translational Medicine

Fig. 2

From: Depurinating estrogen-DNA adducts, generators of cancer initiation: their minimization leads to cancer prevention

Fig. 2

Formation of estrogens, catechol estrogen metabolic pathway and DNA adducts of estrogens. Activating enzymes and depurinating DNA adducts are in red and protective enzymes are in green. N-acetylcysteine (NAC, shown in blue) and resveratrol (Res, shown in burgundy) indicate the various steps where NAC and Res can improve unbalanced estrogen metabolism by reducing formation of depurinating estrogen-DNA adducts

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