Table 2 IC50 values of BI-2536 and nutlin-3 alone and in combination
From: Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma
IC50 values | H295R | SW13 |
|---|---|---|
BI-2536 | 0.0628 µM | 0.0094 µM |
Nutlin-3 | 12.75 µM | 19.78 µM |
Nutlin-3 + BI-2536 | 2.838 µM | 6.502 µM |
Combination Index | 0.22 | 0.33 |