Figure 1
From: Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer
Schematic representation of epithelial-mesenchymal transition. EMT is a process in which epithelial cells disaggregate and exhibit dramatic shape changes. The transitioning epithelial cells lose polarity and intercellular contacts and gain mesenchymal properties such as increased migratory capacity, contractility, and production of extracellular matrix proteins. Common protein markers of epithelial and mesenchymal phenotypes are listed.