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Table 1 Experimental study design

From: Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells

  

Treatment

Group no.

No. of animals per group

Test material

Dose (cells/animal)

Frequency and route

Study period

1

10 (5 males and 5 females)

MSC-NTF cells

1 × 106

1 × IM Injection

4 weeks

2

10 (5 males and 5 females)

MSC-NTF cells

1 × 106

2 × IM Injections

8 weeks

3

10 (5 males and 5 females)

MSC-NTF cells

1 × 106

3 × IM Injections

12 weeks

4

10 (5 males and 5 females)

Vehicle Control

0

3 × IM Injections

12 weeks