Figure 1
From: Possible mechanism and clinical potentials of allostery
Allostery in gene regulation. Effector molecules bind at the protein's allosteric sites, leading to the changes of protein activity. Allostery of protein or DNA then play their respective biological roles through similar signaling pathways in evolution or deleterious physiological process to cause diseases. Targeting signaling pathways or allosteric sites may provide promising therapeutic choices for new drugs.