Table 1 Based on expression data, molecules relevant to oxaliplatin’s mode of action were activated, shown here
From: Network insights on oxaliplatin anti-cancer mechanisms
Multi-targeted effects of oxaliplatin | |
|---|---|
Signaling network | # Up regulated |
Nucleotide Excision Repair | 80% |
RNA Pol II Complex Assembly | 80% |
CHK Related Cell Cycle Control | 70% |
Death Receptor Signaling | 70% |