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Clinical and Translational Medicine

Table 2 Echocardiography and Hemodynamic assessment

From: Peptidomic profiles of post myocardial infarction rats affinity depleted plasma using matrix-assisted laser desorption/ionization time of flight (MALDI-ToF) mass spectrometry

 

Sham (n = 8)

MI + Veh (n = 8)

MI + Ram (n = 8)

Echocardiography data

  

LVIDs (cm)

0.43 ± 0.02

0.89 ± 0.02 ***

0.77 ± 0.02 ###

LVIDd (cm)

0.69 ± 0.01

0.99 ± 0.01 ***

0.94 ± 0.02 #

%FS

38.6 ± 2.1

9.8 ± 1.3 ***

17.2 ± 2.0 #

Hemodynamic data

  

CAP (mmHg)

127.6 ± 1.7

117.1 ± 5.1

104.3 ± 3.4

SBP (mmHg)

146.9 ± 4.0

132.5 ± 4.4

120.1 ± 2.5 #

DBP (mmHg)

106.8 ± 3.3

102.0 ± 6.8

88.9 ± 4.4

HR (beats/min)

348 ± 7

355 ± 29

352 ± 16

LVEDP (mmHg)

2.8 ± 0.7

9.1 ± 1.1 ***

5.5 ± 0.8 #

dP/dt max (mmHg/s)

5898 ± 165

4819 ± 274 *

5156 ± 115

dP/dt min (mmHg/s)

−5851 ± 161

−4637 ± 329 **

−5021 ± 159

  1. LVIDs – left ventricular internal diameter in systole; LVIDd – left ventricular internal diameter in diastole; %FS – percentage fractional shortening; CAP – central aortic pressure; SBP – systolic blood pressure; DBP – diastolic blood pressure; HR – heart rate; LVEDP – left ventricular end diastolic blood pressure; dP/dtmax – rate of left ventricular pressure rise; dP/dtmin – rate of left ventricular pressure fall.
  2. Data are expressed as mean ± SEM; * P < 0.05, ** P < 0.01, *** P < 0.001 compared to sham animals; # P < 0.05, ### P < 0.001 compared to MI + Veh animals.
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