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Clinical and Translational Medicine
Fig. 1 | Clinical and Translational Medicine

Fig. 1

From: Feasibility study of using high-throughput drug sensitivity testing to target recurrent glioblastoma stem cells for individualized treatment

Fig. 1

Course of the disease and time frame for clinical protocol. Glioblastoma patients typically undergo surgery followed by combined radio- and chemotherapy for 6 weeks and thereafter monthly adjuvant chemotherapy. Despite this multimodal treatment the disease almost invariably recurs within 9 months. The time frame for this clinical protocol was defined as 10 weeks following surgery for recurrent GBM, which included expansion of individualized GSC cultures for 6 weeks, automated high-throughput drug screening and data analysis for 1 weeks and scheduling a treatment plan and initiation within 3 weeks

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