Table 3 IC50 values mitotane alone and in combination with BI-2536
From: Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma
IC50 values | H295R | SW13 |
|---|---|---|
Mitotane | 13.45 µM | 7.36 µM |
Mitotane + BI-2536 | 10.49 µM | 13.34 µM |
Combination Index | 0.78 | 1.81 |