Figure 2
From: Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma
Histological characteristics for low grade glioma with KIAA1549-BRAF gene fusions. A. 16–9 gene fusion positive PAs showing a classic histology with low cellularity, minimal pleomorphism, many Rosenthal fibers, microcysts, absence of mitosis and less than 1% MIB-1 positive cells. B. 15–9 gene fusion PAs displaying biphasic low cellular pattern with few Rosenthal fibers and 2-3% MIB-1 index. C. 15–9 PMAs with myxoid background, no Rosenthal fibers, focal angiocentricity and 10% MIB-1 index. D. 15–9, 16–9 positive PAs with no Rosenthal fibers, myxoid background or biphasic pattern and with many gemisytocytes.