Table 2 Vaccination protocols in allergic subjects

Egg

Yellow fever* Rabies* ° Influenza MMR Tick-borne en- cephalitis

MMR and Influenza:

1) If egg-allergy normally administer with a 60 minutes observation

1) Office

2) If egg-anaphylaxis normally administer with a 60 minutes observation

2) Hospital

Yellow fever:

1) If skin tests are negative: normally administer with a 60 minutes observation

Hospital

2) If skin tests are positive: desensitization/graded doses

Cow’s milk

OPV, DTP, DT, DTaP, PCV-13

If previous anaphylaxis normally administer with a 60 minutes observation

Office

Yeasts

Hepatitis B, Quadrivalent HPV, meningococcal , PCV-13, typhoid (oral)

1) If skin tests with vaccine are negative: normally ad- minister with a 60 minutes observation

Hospital

2) If skin tests with vaccine are positive: desensitiza- tion/graded doses

Neomycin

MMR, IPV, rabies, influenza, varicella, Zoster HepA

1) If local skin reaction: normally administer

Office/Hospital

2) If anaphylactic reaction: no vaccine

Gelatin

MMR*, Varicella*, Zooster*, Yellow fever* Rabies °, DTP Influenza

1) If skin tests are negative: normally administered with a 60 minutes observation

Hospital

2) If skin tests are positive: gelatin-free vaccine or de- sensitization/graded doses

Latex

Hospital