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Clinical and Translational Medicine
Figure 2 | Clinical and Translational Medicine

Figure 2

From: Transcriptional factor snail controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma

Figure 2

Cell viability of (A) A2780, (B) A2780cis cells, (C) A2780 shRNA Slug and (D) A2780 shRNA Snail treated with OP at different doses using the WST-1 assay. Cells were incubated in 96 well plates (5000 cells/well) and allowed to adhere for 24 h in 1× DMEM media containing 10% FCS. The media were replaced with fresh DMEM media containing 5% FCS without or with various concentrations of OP for indicated time periods. Cell viability was expressed as a percent of control ± S.E. of triplicate values. The data are a representation of one out of three independent experiments showing similar results. LD50 value is given as μm of drug concentration as determined by WST-1 assay after 48h for each of the cell lines.

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