Fig. 1From: The novel llama-human chimeric antibody has potent effect in lowering LDL-c levels in hPCSK9 transgenic ratsSchematic diagram of the whole experimental workflow. The whole experimental workflow consists of the PCSK9 immunization, blood sampling, VHH library construction, E. coli transformation, phage-display panning, Sanger sequencing, VHHs protein expression, bivalent VHH design, affinity test, LDL-uptake, and pharmacodynamics assayBack to article page