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Table 1 Clinical characteristics of patients in the training cohort and validation cohort

From: Personalized CT-based radiomics nomogram preoperative predicting Ki-67 expression in gastrointestinal stromal tumors: a multicenter development and validation cohort

 

Training cohort

Internal validation cohort

External validation cohort

Low expression

High expression

P*

Low expression

High expression

P*

Low expression

High expression

P*

N = 100

N = 48

 

N = 29

N = 12

 

N = 116

N = 34

 

Age, mean ± SD, years

62.2 ± 12.66

63.08 ± 12.03

0.683

63 ± 13.1

60.17 ± 12.76

0.53

61.81 ± 10.30

59.91 ± 9.99

0.649

Sex

  

1.000

  

0.629

  

0.960

 Female

47 (47.00%)

22 (45.83%)

 

14 (48.28%)

4 (33.33%)

 

71 (61.21%)

20 (58.82%)

 

 Male

53 (53.00%)

26 (54.17%)

 

15 (51.72%)

8 (66.67%)

 

45 (38.79%)

14 (41.18%)

 

Location

  

0.662

  

0.184

  

0.007

 Intestine

37 (37.00%)

21 (43.75%)

 

10 (34.48%)

7 (58.33%)

 

20 (17.24%)

14 (41.18%)

 

 Stomach

63 (63.00%)

27 (56.25%)

 

19 (65.52%)

5 (41.67%)

 

96 (82.76%)

20 (58.82%)

 

Size (cm)

  

< 0.001

  

< 0.001

  

< 0.001

  ≤ 2

13 (13.00%)

1 (2.08%)

 

4 (13.79%)

0 (0%)

 

21 (18.1%)

1 (2.94%)

 

  2–5

54 (54.00%)

13 (27.08%)

 

14 (48.28%)

1 (8.33%)

 

68 (58.62%)

11 (32.35%)

 

  5–10

28 (28.00%)

19 (39.58%)

 

8 (27.59%)

4 (33.33%)

 

27 (23.28%)

15 (44.12%)

 

  > 10

5 (5.00%)

15 (31.25%)

 

3 (10.34%)

7 (58.33%)

 

0 (0)

7 (20.59%)

 
  1. * P value is calculated for difference of clinical characteristics between patients with low expression of Ki67 and patients with high expression of Ki67 by using the univariate analysis