| |
Training cohort
|
Internal validation cohort
|
External validation cohort
|
|---|
|
Low expression
|
High expression
|
P*
|
Low expression
|
High expression
|
P*
|
Low expression
|
High expression
|
P*
|
|---|
|
N = 100
|
N = 48
| |
N = 29
|
N = 12
| |
N = 116
|
N = 34
| |
|---|
|
Age, mean ± SD, years
|
62.2 ± 12.66
|
63.08 ± 12.03
|
0.683
|
63 ± 13.1
|
60.17 ± 12.76
|
0.53
|
61.81 ± 10.30
|
59.91 ± 9.99
|
0.649
|
|
Sex
| | |
1.000
| | |
0.629
| | |
0.960
|
|
Female
|
47 (47.00%)
|
22 (45.83%)
| |
14 (48.28%)
|
4 (33.33%)
| |
71 (61.21%)
|
20 (58.82%)
| |
|
Male
|
53 (53.00%)
|
26 (54.17%)
| |
15 (51.72%)
|
8 (66.67%)
| |
45 (38.79%)
|
14 (41.18%)
| |
|
Location
| | |
0.662
| | |
0.184
| | |
0.007
|
|
Intestine
|
37 (37.00%)
|
21 (43.75%)
| |
10 (34.48%)
|
7 (58.33%)
| |
20 (17.24%)
|
14 (41.18%)
| |
|
Stomach
|
63 (63.00%)
|
27 (56.25%)
| |
19 (65.52%)
|
5 (41.67%)
| |
96 (82.76%)
|
20 (58.82%)
| |
|
Size (cm)
| | |
< 0.001
| | |
< 0.001
| | |
< 0.001
|
|
≤ 2
|
13 (13.00%)
|
1 (2.08%)
| |
4 (13.79%)
|
0 (0%)
| |
21 (18.1%)
|
1 (2.94%)
| |
|
2–5
|
54 (54.00%)
|
13 (27.08%)
| |
14 (48.28%)
|
1 (8.33%)
| |
68 (58.62%)
|
11 (32.35%)
| |
|
5–10
|
28 (28.00%)
|
19 (39.58%)
| |
8 (27.59%)
|
4 (33.33%)
| |
27 (23.28%)
|
15 (44.12%)
| |
|
> 10
|
5 (5.00%)
|
15 (31.25%)
| |
3 (10.34%)
|
7 (58.33%)
| |
0 (0)
|
7 (20.59%)
| |
- * P value is calculated for difference of clinical characteristics between patients with low expression of Ki67 and patients with high expression of Ki67 by using the univariate analysis
