Fig. 5

Critical gene co-expression network modules closely correlated with FGR. a Results of the WGCNA and clustering of the entire transcriptome. b Module size of the gene co-expression network and GO enrichment analyses of 18 modules. c Person correlation analysis of the network modules and continuous demographic characteristics of the FGR infants. The color gradient indicates the direction, i.e., positive (red) and negative (blue), and the strength of the correlation. d Boxplot of stability (Jaccard similarity coefficient) between each module of real data and modules from 1000 bootstrap re-sampling datasets. The line indexes the best-case stability of the random modules in the simulation. e Hierarchical clustering of candidate genes in the representative turquoise module. f Signaling pathway analysis of the turquoise module