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Clinical and Translational Medicine
Fig. 3 | Clinical and Translational Medicine

Fig. 3

From: Whole-transcriptome sequencing uncovers core regulatory modules and gene signatures of human fetal growth restriction

Fig. 3

Differentially expressed miRNAs and physiological functional signaling pathways. a Volcano plot of the differentially expressed miRNAs (11 up-regulated and 2 down-regulated). b The top-30 popular targets as predicted for the critical miRNAs (top-30). c GO enrichment of the predictive targets of the critical miRNAs (top-30). d Signaling pathway enrichment of the predictive targets of the critical miRNAs (top-30). e Specific diseases in TCGA database correlated with the predictive targets of the critical miRNAs (left panel, top-30; right panel, 13 differentially expressed miRNAs). f Clustering and family analyses of the precursors of the critical miRNAs (top-30, red for 13 differentially expressed miRNAs). g Specific diseases correlated with the precursors of the critical miRNAs (top-30, red for 13 differentially expressed miRNAs)

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