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Table 2 Multi-trait analysis results of GWAS for BMD, bone area and SCZ (P value < 1.00 × 10−5)

From: A trans-ethnic two-stage polygenetic scoring analysis detects genetic correlation between osteoporosis and schizophrenia

PhenotypeSNPMAFBetaaP valueaGene
Hip total area vs. SCZ
 SCZrs170183590.23− 0.1013.44 × 10−6CTNNA2
 SCZrs15612960.27− 0.0937.01 × 10−6LOC101927741/SPATS2L
Hip total BMD vs. SCZ
 SCZrs170183590.23− 0.1023.04 × 10−6CTNNA2
 SCZrs15612960.27− 0.0937.53 × 10−6LOC101927741/SPATS2L
Hip neck Area vs. SCZ
 SCZrs170183590.23− 0.1032.81 × 10−6CTNNA2
 SCZrs15612960.27− 0.0937.38 × 10−6LOC101927741/SPATS2L
Hip neck BMD vs. SCZ
 Hip neck BMDrs112594980.09− 0.3061.06 × 10−6LOC105376431 NMT2
 SCZrs170183590.23− 0.1023.09 × 10−6CTNNA2
 SCZrs15612960.27− 0.0937.24 × 10−6LOC101927741/SPATS2L
Spine area vs. SCZ
 Spine arears1745770.41− 0.1752.66 × 10−7 
 Spine arears1745700.41− 0.1724.85 × 10−7 
 Spine arears1745470.42− 0.1705.31 × 10−7 
 Spine arears80194550.22− 0.1892.87 × 10−6 
 SCZrs170183590.23− 0.0994.54 × 10−6 
Spine BMD vs. SCZ
 Spine BMDrs47215640.38− 0.1618.37 × 10−6 
 SCZrs170183590.23− 0.1022.24 × 10−6CTNNA2
 SCZrs169458980.1− 0.1404.19 × 10−6 
 SCZrs15612960.27− 0.0926.70 × 10−6LOC101927741/SPATS2L
 SCZrs17912440.43− 0.0837.17 × 10−6MIR924HG
Ulna & radius area vs. SCZ
 Ulna & radius arears7427150.43− 0.1809.30 × 10−7LOC105377865
 SCZrs170183590.23− 0.1023.05 × 10−6CTNNA2
 SCZrs15612960.27− 0.0937.55 × 10−6LOC101927741/SPATS2L
  1. aThe beta and P value were calculated by MTAG