Table 1 Main characteristics of the included studies in this meta-analysis
Author | Country | Year | Sex M/F | Age mean age ± SD (range age) years | Disease duration mean duration ± SD | BMD measurement | Ulcerative colitis diagnosis | Detection site | Outcome | Cases | Controls | Total | Quality scores |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Krela | Poland | 2018 | 49/56 | 39.6 ± 15.0 | 7.48 ± 7.0 years | DXA | Endoscopic, histopathologic and radiologic criteria | Lumber spine, femoral neck | BMD (g/cm2), T score, Z score, number of low bone density | 105 | 41 | 146 | 7 |
Lima | Brazil | 2017 | 26/42 | 38.2 ± 9.0 | None | DXA | Clinical, endoscopic, histopathologic and radiologic data | Lumber spine and femoral neck | Number of low bone density | 68 | 67 | 135 | 7 |
Bastos | Brazil | 2012 | None | 41.7 ± 14.3 | None | DXA | None | Lumber spine, hip | BMD (g/cm2), number of low bone density | 14 | 40 | 54 | 4 |
Zanetti | Brazil | 2011 | None | (20–50) | None | DXA | None | Lumbar spine, proximal femoral neck and total hip | Number of low bone density | 20 | 44 | 64 | 4 |
Kaya | Turkey | 2011 | 27/13 | 41.53 ± 11.93 | 38.6 ± 36.1 months | DXA | Clinical, endoscopic and histopathological data | Lumber spine, femoral neck | Number of low bone density | 40 | 29 | 69 | 6 |
Pluskiewicz | Poland | 2009 | 20/27 | 47.64 ± 14.83 | 8.6 ± 7.2 years | DXA | None | Lumber spine | BMD (g/cm2), T score, Z score | 47 | 47 | 94 | 7 |
Liu | China | 2009 | None | None | 50 ± 44 months | None | None | None | T score | 43 | 37 | 80 | 3 |
Sakellariou | Greece | 2006 | Male | 25.8 ± 4.6 | None | Ultrasound | Histological finding | Right calcaneous | T score | 14 | 28 | 42 | 6 |
Lamb | UK | 2002 | 15/8 | 45 | < 3 months | DXA | None | Lumber spine, femoral neck | BMD (g/cm2), T score, Z score | 23 | 18 | 41 | 9 |
Ulivieri | Italy | 2001 | 21/22 | Male: 36.5 ± 8.4, Female: 35.3 ± 6.2 | 8 years | DXA | Radiologic, endoscopic and histopathological data | Lumber spine | BMD (g/cm2) | 43 | 111 | 154 | 7 |
Schoon | The Netherlands | 2000 | 24/20 | 38.4 ± 14.4 | 3.4 ± 7.7 months | DXA | Radiologic, endoscopic and histopathological data | Lumber spine, femoral neck | BMD (g/cm2) | 44 | 44 | 88 | 9 |
Dinca | Italy | 1999 | 33/16 | 38 | 8 ± 1 years | DXA | Radiologic, endoscopic and histopathological data | Lumber spine | BMD (g/cm2), T score | 49 | 18 | 67 | 8 |
Jahnsen | Norway | 1999 | 24/36 | 38 | 7 years | DXA | Radiologic, endoscopic and histopathological data | Lumber spine, femoral neck | BMD (g/cm2) | 60 | 60 | 120 | 8 |