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Table 2 Univariate and multivariate analysis for overall survival (OS) for the 304 patients with NPC

From: The prognostic value of integration of pretreatment serum amyloid A (SAA)–EBV DNA (S-D) grade in patients with nasopharyngeal carcinoma

VariablesUnivariate analysisMultivariate analysisa
HR95.0% CI for HRP valueHR95.0% CI for HRP-value
Gender
 Male vs female1.0140.515–1.9970.967
Age
 ≤46 years vs > 46 years1.4580.814–2.6120.205
Tumor stage
 T1–2 vs T3–43.170.976–10.1440.055
Node stage
N0–1 vs N2–31.4971.110–2.0200.008
TNM stage
 I vs II vs III vs IV2.9711.709–5.165<0.0012.1901.234–3.8860.007
Treatment
 Radiotherapy vs chemoradiotherapy3.8000.921–15.6740.065
CRP (mg/L)
 ≤ 2.03 vs > 2.033.0141.496–6.0740.002
SAA (mg/L)
 ≤ 4.46 vs > 4.462.9561.555–5.6170.0012.2761.186–4.3680.013
PLR
 ≤ 141.52 vs > 141.521.3680.767–2.4400.289
NLR
 ≤ 2.62 vs > 2.622.3611.260–4.4260.007
LMR
 ≤ 1.87 vs > 1.871.6190.502–5.2190.420
EBV DNA (copies/mL)
 ≤ 2340 vs > 23403.0791.620–5.8510.0012.0751.061–4.0600.033
  1. aVariables with P < 0.05 in the univariate analysis (Node stage, TNM stage, CRP, SAA, NLR, and EBV DNA) were entered into multivariate analysis