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Fig. 1 | Clinical and Translational Medicine

Fig. 1

From: RANKL/RANK promotes the migration of gastric cancer cells by interacting with EGFR

Fig. 1

RANKL promotes gastric cancer cell migration through RANK. a Western blot showed that RANK protein was expressed in various gastric cancer cells. b The results of flow cytometry showed that there were two peaks of blue and red in gastric cancer cells, indicating that there was a high expression of RANK on the surface of gastric cancer cells. c SGC-7901 and BGC-823 cells were treated with RANKL (1 μg/ml) for 24 h. The transwell assay results showed that the number of cell migration increased significantly. When OPG (10 μg/ml) was added at the same time, the effect of RANKL was cancelled out. d The wound healing assay (magnification, × 100) also confirmed that RANKL can promote gastric cancer migration. Data are mean ± SD in three independent experiment. (**p < 0.01)

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