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Clinical and Translational Medicine
Fig. 4 | Clinical and Translational Medicine

Fig. 4

From: Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer

Fig. 4

Gene ontology (GO) and pathway enrichment analyses of target genes of the identified miRNA biomarkers. a Clusters of miRNA biomarker target-enriched GO terms at the biological process level. In the functional enrichment map, each node refers to a GO term and is grouped based on GO similarity; each edge represents there were shared genes between two connecting GO terms. Node size is determined by the gene number in each GO term. Node color intensity represents enrichment significance. Edge thickness is determined by the number of shared genes between two connecting GO terms. b Top 15 significantly enriched IPA pathways of target genes of the identified miRNA biomarkers

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