TY - JOUR AU - Qi, Xin AU - Yu, Chunjiang AU - Wang, Yi AU - Lin, Yuxin AU - Shen, Bairong PY - 2019 DA - 2019/10/29 TI - Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer JO - Clinical and Translational Medicine SP - 28 VL - 8 IS - 1 AB - High-grade serous ovarian cancer (HGSC), the most common ovarian carcinoma type, is associated with the highest mortality rate among all gynecological malignancies. As chemoresistance has been demonstrated as the major challenge in improving the prognosis of HGSC patients, we here aimed to identify microRNA (miRNA) biomarkers for predicting platinum resistance and further explore their functions in HGSC. SN - 2001-1326 UR - https://doi.org/10.1186/s40169-019-0245-6 DO - 10.1186/s40169-019-0245-6 ID - Qi2019 ER -