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Table 2 Levels of let-7 family members relative to normal tissue in different types of human cancer

From: Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

Let-7 expression in tumors
Let-7 Decreased Increased
Let-7a Hepatoblastoma [70]
Glioma [67]
Ewing sarcoma [85]
Gastric [48]
Nasopharyngeal [70]
Lung [47]
Liver [42, 96]
Melanoma [75]
Endometrial [137]
Cervical [107, 128]
Prostate [138, 139]
Ovarian [43]
 
Let-7b Hepatoblastoma [66]
Liver [42, 96]
Melanoma [75]
Prostate [138, 139]
Ovarian [43]
Let-7c Prostate [58, 139]
Acute promyelocitic leukemia [31]
Liver [42, 96]
Lung [44]
Endometrial [137]
Prostate [138]
Ovarian [43]
Let-7d Oral [62]
Liver [42]
Melanoma [75]
Prostate [138]
Ovarian [140]
Acute promyelocytic leukemia [31]
Let-7e Melanoma [75]
Endometrial [137]
Prostate [138]
Ovarian [140]
Tongue [99]
Esophageal [97]
Let-7f Liver [42]
Endometrial [137]
Prostate [138]
Ovarian [43, 140]
Tongue [99]
Let-7 g HCC [42]
Prostate [138]
Ovarian [43]
 
Let-7i Tongue [99]
Ovarian [141]
Melanoma [75]
Cervical [107]
 
Mir-98 Glioma [71]
Salivary adenoid cystic carcinoma [72]
Prostate [138]
Ovarian [100]
  1. In these experiments, tumors were sampled