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Table 1 Levels of serum let-7 relative to normal control in patients with different types of cancer

From: Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

Let-7 expression in liquid biopsy

Cancer

Increased

Decreased

Breast

let-7a [13]

let-7b [16, 17]

let-7c [17]

let-7i [17]

let-7c [28]

Prostate

let-7a [13]

let-7a [24]

Colon

let-7a [13, 14]

let-7a [21, 22]

let-7b [21]

let-7c [21]

let-7f [22]

let-7i [21]

Renal

let-7a [13]

 

Lung

 

let-7a [23]

let-7b [23]

let-7c [29]

let-7f [26]

let-7ia [15]

Gastric

let-7f [19]

let-7i [19]

let-7a [25]

Liver

let-7b [15]

let-7f [18]

 

Ovarian

let-7b [134]

let-7f [27]

let-7i [135]

Thyroid

let-7e [136]

 
  1. In these experiments, liquid biopsies (from blood) were sampled
  2. aAssociated with smoking