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Table 2 Clinical and laboratory features of anticytokine seropositive SS cases

From: Clinical features of Sjögren’s syndrome patients with autoantibodies against interferons

Case

Cytokine autoantibodies

Clinical features

ANA

ENA

RF

Schirmer’s

13

Low IFN-ω

 

Pos

Pos

Pos

Pos

14

Low IFN-ω

Hashimoto’s thyroiditis, lymphoma

Pos

Pos

Pos

Pos

24

Mod IFN-γ

 

Pos

Pos

Pos

Pos

31

Low IFN-ω

Hypothyroidism, anti-ds DNA+, pANCA+

Pos

Pos

Pos

Pos

45

Mod IFN-α and -ω

Pulmonary hypertension

Pos

Pos

Pos

Pos

47

Low IFN-ω

Anti-centromere autoantibodies

Pos

Pos

Pos

Pos

56

High IFN-α and -ω

 

Pos

Pos

Pos

Neg

63

Mod IFN-γ

Peripheral neuropathy

Pos

Pos

Pos

Pos

69

High GMCSF

 

Pos

Pos

Pos

Neg