Fig. 3
From: Clinical features of Sjögren’s syndrome patients with autoantibodies against interferons
Clinical correlates of cytokine autoantibodies in SS. The SS cohort was stratified based on the 48 SS subjects with cytokine autoantibody seronegative status (Cyt AAB−), or 9 SS subjects with cytokine autoantibody seropositive status (Cyt AAB+). The color coding of the cytokine seropositive samples corresponds to their display in Fig. 1. The SS subject (#56) with partially neutralizing autoantibodies to interferon-α is shown by the red diamond. a Ro52 and b La autoantibodies were measured by LIPS and analyzed. The dotted line is based on cut-off value from HV. Mann–Whitney U test was used for statistical analysis. c The focus score, a histological marker assessment of the amounts of inflammatory cells in the salivary gland biopsy and d unstimulated salivary flow for the subjects is shown for the HV, Cyt AAB− and Cyt AAB+