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Table 2 This table indicates the appropriate uses for each type of murine OA model. An X indicates that a model is appropriate for a specific type of study

From: Pros and cons of mouse models for studying osteoarthritis

  OA pathophysiology OA progression OA therapies Pain behavior Post-traumatic OA studies References
Naturally occurring X X X X   [9,10,11]
Genetically modified X X X X   [12,13,14,15,16,17,18,19,20,21,22,23,24]
Surgically induced (all) X X X X X [25,26,27,28,29,30]
Chemically induced (all)     X   [31,32,33,34,35,36,37,38,39]
Non-invasive induction X X X X X [40,41,42,43,44,45,46,47,48,49,50,51,52]