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Fig. 3 | Clinical and Translational Medicine

Fig. 3

From: HIV-exposed uninfected infants: elevated cord blood Interleukin 8 (IL-8) is significantly associated with maternal HIV infection and systemic IL-8 in a Kenyan cohort

Fig. 3

Maternal HIV infection drives infant IL-6 and IL-8 levels present at birth in HEU infants through different pathways. SEM models with maternal HIV infection (yes/no), maternal IL-8 levels at delivery in the pathway, and infant cord blood IL-8 levels as the outcome variable for 42 mother-infant pairs. HEU infants have 2.38 ln IL-6 levels in cord blood at birth and none of the infant IL-6 is attributable to maternal IL-6 levels (a). HEU infants have 3.75 times ln IL-8 levels in cord blood than detected in HU cord blood, and ~ 23% of this can be attributed to the maternal IL-8 levels (b)

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