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Clinical and Translational Medicine
Fig. 1 | Clinical and Translational Medicine

Fig. 1

From: HIV-exposed uninfected infants: elevated cord blood Interleukin 8 (IL-8) is significantly associated with maternal HIV infection and systemic IL-8 in a Kenyan cohort

Fig. 1

HIV exposed uninfected infant cord blood displays elevated cytokines consistent with inflammation and immune stimulation compared to HIV unexposed infant cord blood. Cytokines were detected in samples from all maternal delivery plasma and infant cord blood plasma using multiplexed Luminex Elisa bead-based technology. Assays at or below the lower limit of detection were assigned the lowest limit of detection. Individual plasma concentration (ln pg/ml), group median and IQR are plotted. Related sample medians (HEU vs HIV+ mother, n = 23 pairs; HU vs HIV− mother, n = 19 pairs) were compared using Wilcoxon Rank Sum test while independent medians were compared using Mann–Whitney U test (HEU vs HU). Symbols are as follows: HIV− women filled squares, HU infants open squares, HEU infants open circles, HIV+ women filled circles

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