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Clinical and Translational Medicine

Table 3 Comparison for baseline severity of disease, demographics and mortality between patients with Runx1p66/p52 high ratio vs. patients Runx1p66 negative or low Runx1p66/p52 ratio

From: Alk5/Runx1 signaling mediated by extracellular vesicles promotes vascular repair in acute respiratory distress syndrome

 

Runx1 p66/p52 high ratio

Low Runx1 p66/p52 ratio or p66 negative

p value

No.

17

12

–

Mortality

3 (17.6%)

7 (58.33)

0.023 (OR = 5.15)

Age

41.76 ± 6.4

50.25 ± 9.4

0.142

Sex

10F/7M

5F/7M

0.362

SAPS II

47.23 ± 6.9

53.33 ± 7.25

0.254

APACHE II

23 ± 3

25.5 ± 4.35

0.349

SOFA

10.94 ± 1.58

13.08 ± 2.18

0.124

Lung Injury Score

2.91 ± 0.33

3.09 ± 0.49

0.574

P/F ratio at onset of ARDS

118.13 ± 25.04

96.04 ± 19.21

0.213

ICU length of stay

28.76 ± 10.05

22.42 ± 13.66

0.460

  1. APACHE II Acute Physiology and Chronic Health Evaluation II; SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment score, LIS Lung Injury Score, P/F PaO2/FiO2 ratio on the day of diagnosis of ARDS; Values are mean ± SD
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