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Fig. 2 | Clinical and Translational Medicine

Fig. 2

From: Cancer; an induced disease of twentieth century! Induction of tolerance, increased entropy and ‘Dark Energy’: loss of biorhythms (Anabolism v. Catabolism)

Fig. 2

Schematic representation of ontology of fetal growth, showing vasculogenesis and organogenesis, under placenta’s limited oxygen tension. It depicts that fetus growth occur primarily in the absence of functional mitochondria and Yin (tumoricidal, high energy) arm of effective immunity. After birth and exposure to atmospheric oxygen and environmental hazards, adaptation, reprogramming and completion of organ development, formation of lymphoid organs, immune cell maturation and migration in thymus and bone marrow are required, for functionality of mitochondria and effective immunity (Yin–Yang). As depicted, requirements for differential bioenergetics and effective immunity, cell mediated or humoral immunity (CMI, HI), to defend body against harmful elements throughout life occur after birth. See text

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