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Fig. 2 | Clinical and Translational Medicine

Fig. 2

From: Cancer nanomedicine: a review of recent success in drug delivery

Fig. 2

(Reproduced with permission from [3])

Types of targeting for nanoparticle delivery to tumor tissue. a Passive targeting relies on the leaky vasculature that is exhibited by tumors, allowing nanoparticles to travel through the fenestrations and reach tumors. b Active targeting can be used when nanoparticles have ligands on their surface that can recognize and bind receptors that are overexpressed on tumor cells. c Triggered release allows nanoparticles to congregate if exposed to an external stimulus such as a magnetic field or light

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