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Table 8 Shared and unshared structural variation (SV) as compared to NCBI Build 37

From: Post-zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia

Sample Total SVs Shared with co-twin Unshared with co-twin Shared with co-twin Unshared with co-twin
Inherited De novo Inherited De novo
Family 1 affected (I-2-1) 919 781 138 750 31 97 41
Family 1 unaffected (I-2-2) 893 781 112 750 31 66 46
Family 2 affected (II-2-1) 996 855 141 N/A N/A N/A N/A
Family 2 unaffected (II-2-2) 977 855 122 N/A N/A N/A N/A
  1. Structural variants fell under five categories: deletions, tandem duplications, distal duplications, inter-chromosomal variations and inversions. There were no inversion differences found between twins in either family. They were not included in subsequent analyses