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Table 6 Utilisation of lipid lowering medications among T2DM patients

From: Profiling of cardio-metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study

Variable

Baseline

Follow up

Mean difference (95% CI)

p value

% difference

TC (mmol/l)

 No statin

5.03 ± 0.12

4.95 ± 0.13

−0.07 (−0.42 to 0.28)

0.6817

1.39

 Atorvastatin

4.06 ± 0.16

4.13 ± 0.16

0.07 (−0.37 to 0.51)

0.7434

1.72

TG (mmol/l)

 No statin

1.32 ± 0.06

1.19 ± 0.06

−0.13 (−0.30 to 0.04)

0.1322

9.85

 Atorvastatin

1.14 ± 0.06

0.93 ± 0.06

−0.21 (−0.39 to −0.03)

0.0259

18.42

HDL-c (mmol/l)

 No statin

1.36 ± 0.03

1.05 ± 0.03

−0.30 (−0.39 to −0.21)

<0.0001

22.06

 Atorvastatin

1.36 ± 0.04

1.04 ± 0.04

−0.31 (−0.42 to −0.19)

<0.0001

22.79

Non-HDL (mmol/l)

 No statin

3.67 ± 0.11

3.89 ± 0.12

0.23 (−0.09 to 0.55)

0.1617

6.27

 Atorvastatin

2.69 ± 0.15

3.09 ± 0.15

0.39 (−0.04 to 0.81)

0.0754

14.50

LDL-c (mmol/l)

 No statin

3.06 ± 0.11

3.36 ± 0.11

0.30 (−0.01 to 0.60)

0.058

9.80

 Atorvastatin

2.19 ± 0.15

2.68 ± 0.14

0.47 (0.06 to 0.87)

0.022

21.46

CR

 No statin

5.24 ± 0.15

5.57 ± 0.49

0.33 (−0.68 to 1.34)

0.5202

6.29

 Atorvastatin

4.31 ± 0.19

4.32 ± 0.20

0.02 (−0.53 to 0.57)

0.9547

0.46

VLDL-c (mmol/l)

 No statin

0.60 ± 0.03

0.58 ± 0.05

−0.01 (−0.12 to 0.09)

0.8181

1.67

 Atorvastatin

0.52 ± 0.03

0.42 ± 0.03

−0.09 (−0.18 to −0.01)

0.0237

17.3

  1. CI confidence interval
  2. p < 0.05 is considered significant