Fig. 2
From: The role of heterogeneity in asthma: a structure-to-function perspective
(reproduced with permission from [19])
Modeled lung resistance (a) and lung elastance (b) derived from an airway tree model. Homogeneous constriction leads to a uniform elevation in RL and significant shunting into the compliant central airways presenting as a progressive increase in EL with frequency. Heterogeneous constriction leads to an increased frequency dependence in both RL and EL