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Table 6 Association between CXCL9-11 haplotypes and liver fibrosis stage in HCV-infected patients

From: CXCL9-11 polymorphisms are associated with liver fibrosis in patients with chronic hepatitis C: a cross-sectional study

 

CXCL9-11 Haplotypes

Association

p

rs10336

rs3921

rs4619915

Freq.

aOR (95% CI)

F ≥ 2 (≥7.1 kPa)

G

G

G

0.581

0.95 (0.70; 1.30)

0.760

 

A

C

A

0.401

1.01 (0.74;1.39)

0.929

 

A

G

G

0.011

2.50 (0.59;10.5)

0.198

F ≥ 3 (≥9.5 kPa)

G

G

G

0.581

0.97 (0.70;1.36)

0.868

 

A

C

A

0.401

1.10 (0.78;1.54)

0.597

 

A

G

G

0.011

0.32 (0.04;2.64)

0.226

F4 (≥12.5 kPa)

G

G

G

0.581

0.91 (0.62;1.34)

0.629

 

A

C

A

0.401

1.12 (0.76;1.66)

0.557

 

A

G

G

0.011

0.58 (0.07;4.85)

0.591

  1. Statistical: p values were calculated by multivariate logistic regression adjusted by the most important clinical and epidemiological characteristics
  2. 95% CI 95% of confidence interval, aOR adjusted odds ratio, p value level of significance, F  2 significant fibrosis, F  3 advance fibrosis, F4 cirrhosis, HCV-GT hepatitis C virus genotype, CXCL chemokine (C-X-C motif) ligand