Clinical and Translational Medicine

Table 2 Summary of Hardy–Weinberg Equilibrium test and allelic and genotypic frequencies genotypes for CXCL9-11 polymorphisms in HCV-infected patients compared to Iberian population (data from HapMap) (http://browser.1000genomes.org/index.html)

From: CXCL9-11 polymorphisms are associated with liver fibrosis in patients with chronic hepatitis C: a cross-sectional study

SNPs	HCV cohort (n = 389)					IBS group (n = 107)					χ² test^a	χ² test^b
SNPs	HWE	Alleles		Genotype		HWE	Alleles		Genotype		p value	p value
CXCL9 rs10336	0.738	A	41%	AA	16%	0.677	A	45%	AA	22%	0.568	0.556
		G	59%	AG	50%		G	55%	AG	46%
				GG	34%				GG	32%
CXCL10 rs3921	0.841	C	41%	CC	16%	0.884	C	45%	CC	21%	0.568	0.653
		G	59%	CG	49%		G	55%	CG	47%
				GG	35%				GG	32%
CXCL11 rs4619915	0.841	A	41%	AA	16%	0.884	A	44%	AA	21%	0.668	0.650
		G	59%	AG	49%		G	56%	AG	45%
				GG	35%				GG	34%

Statistical: p values were calculated by Chi squared test
HWE Hardy–Weinberg Equilibrium, HCV hepatitis C virus, IBS Iberian populations in Spain, CXCL chemokine (C-X-C motif) ligand
^aDifferences between allele frequencies
^bDifferences between genotype frequencies

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