Fig. 2
From: Significance of long chain polyunsaturated fatty acids in human health
Principal bioactive lipid mediators derived from ARA, EPA and DHA by the action of lipoxygenases (LOXs), cyclooxygenases (COXs), cytochrome P450 (CYP-450) and soluble epoxide hydrolase (sEH). ARA (arachidonic acid), DHA (docosahexaenoic acid), DHET (dihydroxy-eicosatrienoic acid), DiHDPA (dihydroxy-docosapentaenoic acid), DiHETE (dihydroxy-eicosatetraenoic acid), EET (epoxy-eicosatrienoic acid), EPA (eicosapentaenoic acid), EpDPE (epoxy-docosapentaenoic acid), EpETE (epoxy-eicosatetraenoic acid), HEPE (hydroxy-eicosapentaenoic acid), HETE (hydroxy-eicosatetraenoic acid), HpDHA (hydroperoxy-docosahexaenoic acid), HpEPE (hydroperoxy-eicosapentaenoic acid), HpETE (hydroperoxy-eicosatetraenoic acid), LT (leukotriene), LX (lipoxin), PG (prostaglandin), Rv (resolvins), TX (thromboxane)