Fig. 2

Analysis of cardiopulmonary functions of conscious, spontaneously breathing, unrestrained rats placed in whole-body barometric flow-plethysmographs (food and water accessible) from the end of exposure to phosgene until the next morning during a data collection-period of 20 h. Measurements focused on respiratory rate, enhanced pause (Penh) and heart rate using radiotelemetry transmitters intra-peritoneally placed in a single lead II configuration (DSI PhysioTel^® Implantable Telemetry System). Data represent means ± SD from eight rats/group (averaged during collection periods of 15 min). Insert (mid panel): Penh is a unitless index that was used to evaluate changes in the shape of the airflow patterns as index of changes in the control of breathing secondary to ALI