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Clinical and Translational Medicine
Fig. 3 | Clinical and Translational Medicine

Fig. 3

From: Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?

Fig. 3

In vivo seeding efficiency assay for human cells. Human cells exposed ex vivo (primed) to a pro-metastatic factor or a receptor blocking agent are subsequently injected i.v. into immunodeficient mice. Mice can be additionally irradiated with 360 cGy. The number of human cells can be detected in murine organs by FACS (after labelling cells with fluorochrome or transducing with GFP) or by detecting the level of human DNA in murine organs

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