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Clinical and Translational Medicine
Fig. 5 | Clinical and Translational Medicine

Fig. 5

From: A quantitative metabolomics profiling approach for the noninvasive assessment of liver histology in patients with chronic hepatitis C

Fig. 5

Clinical applicability of the advanced fibrosis (F3–4), necroinflammation and the steatotic model based on the receiver operator curve. a For the advanced fibrosis model, the AUROC is 0.86 (95 % CI 0.74–0.97). b Accuracy of the model based on the cross-validated score and the fibrosis stage. Accuracy of the model is 82 % with a sensitivity, specificity, positive predictive value and negative predictive value of 80, 83, 71 and 89 % respectively. c Shows the receiver operator characteristic (ROC) curve for the necroinflammation model with an AUROC of 0.73 (95 % CI 0.57–0.89). d Receiver operator characteristic (ROC) curve for the steatotic model with an AUROC of 0.87 (95 % CI 0.76–0.97)

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